Condition Info - BotMed Application

ConditionName

Acute Pancreatitis

ConditionDescription

Symptoms

Sudden onset; Epigastric pain; Radiates to back; 
Pain is steady and boring in quality; 
NOT POSITION DEPENDENT;
History of cholelithiasis or excessive alcohol us; 
Nausea; Vomiting; Diaphoresis;
Low grade fever; abdominal distension;

PhysicalFindings

Cullen sign; Grey Turner sign;
Hypoxia, hypocalcemia (b/c fat malabsorption);
Hypoactive bowel sounds;

ClinicalTests

Initial: CBC (leukocytosis; Hct); dehydration and Hct very concentrated; Amylase and lipase (>3x); lipase - more specific. 
Most specific: CT with IV contract(enlarged pancreas; pseudocyst) or MRI; US: gallstones cause; 

Liver panel, bilirubin; 
↑ LDH; ↑ AST; 
Hypocalcaemia (b/c fat malabsorption);

RiskFactors

Alcohol abuse; 
Smoking;
Gallstones; 
Trauma; 
Mumps and other infections; 
Autoimmune; 
Scorpion string; 
Hypertriglyceridemia; 
Hypercalcemia; 
ERCP; 
Drugs (Steroids, Azathioprine and 6-Mercaptopurine, GLP-1,  DPP-4 inhibitors, 5-ASA and Derivatives, Antibiotics ( metronidazole, tetracyclines)
Valproic acid (VPA);
Idiopathic;

IsRedFlag

IsNPLEX

Consequence

Often requires hospitalization in 48h;

ProgressionFromCondition

Gall stones;
Alcohol abuse;
High triglyceride levels above 1000 mcg/mL (500 mcg/mL for first episode).

TreatmentOptions

NPO – no food!
IV hydration;
Emergency;

PharmOptions

Analgesia;
PPI;
>30% necrosis on CT –> add antibiotics;
Surgery;

WebLink

https://www.merckmanuals.com/professional/gastrointestinal-disorders/pancreatitis/acute-pancreatitis