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Condition Info
ConditionName
Diabetic ketoacidosis (DKA)
ConditionDescription
Symptoms
Generalized abdominal pain in children; Hyperventilation; Polydipsia; polyuria; weakness; Altered mental status; Dry mucous membranes; decreased skin turgor; Fruity odor; Nausea and vomiting; but no diarrhea;
PhysicalFindings
Kussmaul respirations
ClinicalTests
Measure of severity: serum bicarb; ↑K in blood, but ↓total body K (without insulin K can’t enter the cell), ↑K in urine; ↑serum for ketones; ↑Glucose (300-800); High anion gap metabolic acidosis;
RiskFactors
IsRedFlag
IsNPLEX
Consequence
ProgressionFromCondition
DM 1, sometimes DM2 in combination of: Infections (pneumonia, GE, UTI); Medication; MI, CVA, trauma; Dehydration; Alcohol; Drug abuse; Steroids --> dehydration --> DKA;
TreatmentOptions
Correct underline cause (medication, infection);
PharmOptions
Large isotonic and insulin replacement; Replace K when level of K come down (IV K) and other electrolytes (Ca, Mg, P);
WebLink
https://www.merckmanuals.com/professional/endocrine-and-metabolic-disorders/diabetes-mellitus-and-disorders-of-carbohydrate-metabolism/diabetic-ketoacidosis-dka
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