Condition Info - BotMed Application

ConditionName

Crohn Disease (IBD)

ConditionDescription

Symptoms

LLQ; RLQ pain; Crampy abdominal pain; Chronic diarrhea (which sometimes is bloody when the large intestine is severely affected; helps to DDx with appendix)); Fever; Anorexia; Weight loss; Inflammation;

PhysicalFindings

Oral lesions; Erythema nodosa on the anterior legs; RLQ ab mass; Abdominal tenderness; Chronic anorexia;
Fever; Perianal fissures and fistulas; Oral ulcers

ClinicalTests

Barium study; abdominal CT;
Calprotectin stool test (IBS>50, IBD>150) --> not diagnostic;
Colonoscopy with biopsy: Skip lesions; Transmural granulomas; Fistulas and granulomas; Masses and obstructions; Perianal dz; affects terminal ilium;
Endoscopy: Inflammation.

RiskFactors

Caucasians;
Jewish;
Family history;
HLA-B27+;

IsRedFlag

IsNPLEX

Consequence

Malabsorption;
Fissures;
Structures;
Abscess formation;
Megaloblastic anemia;
B12 def;
Iron def;

ProgressionFromCondition

TreatmentOptions

Surgery (rare);
In addition to CD treatment:
Topical treatment with supp and enema;
Iron for anemia;

PharmOptions

Steroids with of without antibiotics;
Azathioprine;
Anti-TNFa agents (infliximab);

WebLink

https://www.merckmanuals.com/professional/gastrointestinal-disorders/inflammatory-bowel-disease-ibd/crohn-disease?query=Crohn Disease