Condition Info - BotMed Application

ConditionName

Polymyositis

ConditionDescription

Proximal muscle weakness. Difficulty to move from sitting position and moving uptears.

Symptoms

Do not affect facial muscles;
Dysphasia;
Symmetric progressive, proximal muscle weakness;
Occurs in legs first;
Myalgias;
Muscle atrophy (later stages);

PhysicalFindings

ClinicalTests

Best initial test: ↑CPK and aldolase;
↑ALT, AST;

Most accurate test: muscle biopsy;

Anti-Jo-1 Abs;
ANA frequently positive;

MRI: patch muscle involvement;

Electromyography abnormal;

Muscle biopsy ;

RiskFactors

Increased risk of cancer;
Interstitial lung dz;

IsRedFlag

IsNPLEX

Consequence

ProgressionFromCondition

TreatmentOptions

PharmOptions

Steroids;
Methotrexate;
IVIG;

WebLink

https://rarediseases.info.nih.gov/diseases/7425/polymyositis