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Condition Info
ConditionName
Gilbert syndrome
ConditionDescription
Symptoms
1/3 are asymptomatic; Abdominal pain; Jaundice; Fatigue; Loss of appetite; Feeling sick; Dizziness; A general sense of feeling unwell;
PhysicalFindings
ClinicalTests
ALT/AST - normal; Bilirubin - elevated (indirect (unconjugated)) Presence of hyperbilirubinemia in the absence of hemolysis; mild decrease in the activity of the enzyme glucuronosyltransferase, causing an increase in the indirect (unconjugated) fraction of serum bilirubin
RiskFactors
3% to 7% of Americans have Gilbert's syndrome;
IsRedFlag
IsNPLEX
Consequence
Irritable bowel syndrome (IBS);
ProgressionFromCondition
These things can raise bilirubin levels in people with Gilbert's syndrome, leading to jaundice: Dehydration; Fasting or skipping meals; Illness or infections; Overexertion (too much physical activity); Stress; Drinking too much alcohol (keep within the recommended weekly units of alcohol); Not getting enough sleep Having surgery; Menstruating; Having a period; Exposure to cold temperatures;
TreatmentOptions
PharmOptions
WebLink
https://www.nhs.uk/conditions/gilberts-syndrome/
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