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Condition Info
ConditionName
Cholangitis
ConditionDescription
Symptoms
Charcot triad: RUQ pain; Jaundice; Fever; Reynolds pentad: + Altered mental status; Hypotension or shock
PhysicalFindings
Hepatomegaly; Low BP
ClinicalTests
↑WBC; ↑ALP; ↑bilirubin; ↑AST↑ALT; ↑amylase; US ok’ but HIDA scan is better; Blood culture (if infection suspected); Most accurate: Endoscopic retrograde cholangiopancreatography (ERCP), or magnetic resonance cholangiopancreatography (MRCP);
RiskFactors
IsRedFlag
IsNPLEX
Consequence
Gall stone; Cirrhosis; Ascites; Edema; Portal hypertension; Bacteremia --> antibiotics;
ProgressionFromCondition
Blockage and inflammation of the main hepatic duct;
TreatmentOptions
Hydration; Endoscopic biliary drainage; Delayed cholecystectomy;
PharmOptions
IV antibiotics;
WebLink
https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/gallbladder-and-bile-duct-disorders/primary-sclerosing-cholangitis-psc
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