Condition Info - BotMed Application

ConditionName

Paget Disease of Bone (Paget's Disease of Bone; Osteitis Deformans)

ConditionDescription

Overactive osteoclasts and osteoblasts

Symptoms

Bone pain;
↑fractures;
Pelvis. Paget's disease of bone in the pelvis can cause hip pain.
Skull. An overgrowth of bone in the skull can cause hearing loss or headaches.
Spine. If your spine is affected, nerve roots can become compressed. This can cause pain, tingling and numbness in an arm or leg.
Leg. As the bones weaken, they may bend — causing you to become bowlegged. Enlarged and misshapen bones in your legs can put extra stress on nearby joints, which may cause osteoarthritis in your knee or hip.

PhysicalFindings

Bowing of tibia;
Kyphosis;
Narrowing of auditory foramen;
↑cranial diameter;

ClinicalTests

Plain x-rays – most sensitive test;
Bone scan;
↑alkaline phosphatase;
Normal Ca and P;

RiskFactors

IsRedFlag

IsNPLEX

Consequence

ProgressionFromCondition

TreatmentOptions

Self limited;

PharmOptions

WebLink

https://www.merckmanuals.com/en-ca/professional/musculoskeletal-and-connective-tissue-disorders/paget-disease-of-bone/paget-disease-of-bone