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Condition Info
ConditionName
Disseminated Intravascular Coagulation (DIC)
ConditionDescription
Deposition of fibrin I small vessels leading to end organ damage.
Symptoms
Never in healthy people; Uncontrolled bleeding; Hemoptysis; Jaundice;
PhysicalFindings
ClinicalTests
R/O: Severe liver dz; D-dimer; ↑PT and PTT; ↓platelets count; ↑BT; ↓fibrinogen; All factors are low;
RiskFactors
Sepsis; Burns; Abruptio placenta or amniotic fluid embolus; Trauma resulting in tissue factor release; Cancer; Snake bite; Clotting factor def as well as thrombocytopenia; Adenocarcinoma;
IsRedFlag
IsNPLEX
Consequence
ProgressionFromCondition
STOP Making Thrombi: Sepsis; Trauma; OB complications; Pancreatitis; Malignancy; Transfusion;
TreatmentOptions
Decrease fibrinogen level; Treat underline problem;
PharmOptions
Heparin has no benefits;
WebLink
https://www.merckmanuals.com/en-ca/professional/hematology-and-oncology/coagulation-disorders/disseminated-intravascular-coagulation-dic
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