Condition Info - BotMed Application

ConditionName

Multiple myeloma

ConditionDescription

Abnormal proliferation of plasma cells.

Symptoms

Bone pain, especially in your spine or chest.
Nausea.
Constipation.
Loss of appetite.
Mental fogginess or confusion.
Fatigue.
Frequent infections.
Weight loss.

Bone pain from pathologic fracture;
Radicular pain – from compression;

Anemia; Pallor
From high Ca: polyuria, polydipsia, altered mental status;

PhysicalFindings

ClinicalTests

First test: x-Ray (lytic lesion) back or ribs;
Makes IgG and IgA;
M spike of electrophoresis (see monoclonal Igg spike);

Anemia ↓WBC;
Renal insufficiency;

OAF -> hypercalcemia (mild the bone);

Most accurate test: plasma cells on bone marrow biopsy >10%;

Rouleaux – in blood smear;

Decrease anion gap;

RiskFactors

IsRedFlag

IsNPLEX

Consequence

Infections b/c no immunoglobulins against infection;

Renal failure and anemia;

Spinal cord compression;

Systemic complications bone, KI, infections;

C - Ca;
R - renal;
A - anemia;
B – bones damages;

ProgressionFromCondition

<70 --> auto steam cells transplant;

TreatmentOptions

For older prednisone;

PharmOptions

WebLink

https://www.merckmanuals.com/professional/hematology-and-oncology/plasma-cell-disorders/multiple-myeloma