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Condition Info
ConditionName
Nephrotic syndrome
ConditionDescription
Symptoms
Severe swelling (edema), particularly around your eyes and in your ankles and feet. Weight gain due to fluid retention. Fatigue. Loss of appetite. Dyspnea (pleural effusion or laryngeal edema); Arthralgia (hydrarthrosis); Abdominal pain (ascites or, in children, mesenteric edema);
PhysicalFindings
ClinicalTests
Urine random (spot) protein/creatinine ratio ≥ 3 or proteinuria ≥ 3 g/24 hours; CBC Kidney and liver function, serum albumin; PT/INR, PTT; Fasting glucose, HbA1C; Antinuclear antibody; Electrolytes; Foamy urine, a result of excess protein in your urine.
RiskFactors
HIV; Hepatitis B, hepatitis C; Syphilis; Malaria; Cancer (lung, breast, prostate, colon cancer); Hodgkin lymphoma; Drugs: NSAIDs, ACE, tamoxifen, lithium, heroin;
IsRedFlag
IsNPLEX
Consequence
DVT; PE;
ProgressionFromCondition
TreatmentOptions
PharmOptions
WebLink
https://www.merckmanuals.com/en-ca/professional/genitourinary-disorders/glomerular-disorders/overview-of-nephrotic-syndrome
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