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Condition Info
ConditionName
Breast cancer
ConditionDescription
Symptoms
Mass solid and immobile; Peau d’orange; New nipple retraction; Dimpling of the breast.
PhysicalFindings
Axillary lymphadenopathy
ClinicalTests
Mammogram (screening test); CA 15-3; Biopsy: FNA, but better core biopsy;
RiskFactors
Family history; Mutation BRCA1 and BRCA2; Estrogen exposure; Early menses, late menopause, nulliparty, Late 1st pregnancy, HRT Age; Obesity; Alcohol; Certain chemicals + pesticides; Most common side: Upper outer Q.
IsRedFlag
IsNPLEX
Consequence
Metastasis: Bone; Thorax; Brain; Liver. Lymphedema;
ProgressionFromCondition
Metastatic dz or large tumor (>1 cm) or aggressive tumor: chemotherapy; Hormonal therapy: tamoxifen (positive for Est and Progesterone); Positive for HER2/neu: Trastuzumab; BRCA mutation: bilateral prophylactic mastectomies;
TreatmentOptions
PharmOptions
WebLink
https://www.merckmanuals.com/en-ca/professional/gynecology-and-obstetrics/breast-disorders/breast-cancer
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