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Condition Info
ConditionName
Ovarian cancer
ConditionDescription
Symptoms
Often asymptomatic early; None – most are detected when disseminated; Nonspecific abdominal symptoms; Bloating, worse around evening; Nausea, dyspepsia; Anorexia, early satiety; Only later: abdominal pain, fatigue, weight loss, change in bowel habits, menstrual irregularities, ascites; Increased abdominal girth from ascites or tumour Urinary frequency or constipation (mass effect)
PhysicalFindings
Palpable mass on bimanual exam (may be)
ClinicalTests
CA-125 (screening test); Transvaginal (TV) ultrasound (screening test); CT abdomen and pelvis; Liver enzymes; CBC;
RiskFactors
Family history (BRCA1, BRCA2); Nulliparity; Early menarche; Late menopause; Infertility;
IsRedFlag
IsNPLEX
Consequence
Metastases: Liver, spleen, pleura, peritoneum.
ProgressionFromCondition
Breast cancer; Endometrial cancer; Colon cancer;
TreatmentOptions
Surgical resection; Pregnancy decreases risk;
PharmOptions
Protective factors: OCP
WebLink
https://www.merckmanuals.com/en-ca/professional/gynecology-and-obstetrics/gynecologic-tumors/ovarian-cancer
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