Condition Info - BotMed Application

ConditionName

Cirrhosis

ConditionDescription

Symptoms

Compensated: Weight loss; Fatigue; Loss of appetite; Nausea;

Decompensated: Yellow discoloration in the skin and eyes (jaundice); Easily bleeding or bruising; Swelling in your legs, feet or ankles (edema); Itchy skin;

PhysicalFindings

Caput medusae;
Splenomegaly;
Gynecomastia;
Spider angiomata; 
Ascites;
Palmar erythema;
Digital clubbing;
Asterixis;
Normal or low JVP
Splenomegaly

ClinicalTests

↑ALT and AST;
↓Albumin;
Anemia;
↓Platelets;
↑PT and PTT;
High estrogen;
High conjugated bilirubin;
Low Na;
High creatinine;

Gold standard: Liver biopsy;
US: small nodular liver;

Hepatitis B and C serologies;
Liver biopsy

RiskFactors

Alcohol consumption;
Hepatitis C, B;
Bile duct obstruction, chronic cholestasis (PBC, PSC);
Hemochromatosis;
Wilson disease;
NAFLD;
Autoimmune hepatitis;

IsRedFlag

IsNPLEX

Consequence

High ammonia;
Portal HTN;
Wilson disease;

ProgressionFromCondition

Liver failure;
Wilson disease

TreatmentOptions

Stop to drink alcohol;
Lactulose helps to clean up ammonia;
Liver transplant;

PharmOptions

WebLink

https://www.merckmanuals.com/en-ca/professional/hepatic-and-biliary-disorders/fibrosis-and-cirrhosis/cirrhosis