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Condition Info
ConditionName
Hemolytic anemia
ConditionDescription
Symptoms
Pallor, fatigue, dizziness, possible hypotension. Possible jaundice, and the spleen may enlarge. Hemolytic crisis (acute, severe hemolysis) is uncommon: chills, fever, pain in the back and abdomen, prostration, shock. Hemoglobinuria causes red or reddish-brown urine.
PhysicalFindings
ClinicalTests
All have: normal MCV; ↑reticulocytes; ↑LDH, ↑indirect bilirubin (can’t go to urine it’s attached to albumin); Peripheral smear – very helpful; Sudden ↓Hct; ↑LDH, ↑indirect bilirubin (can’t go to urine it’s attached to albumin); ↑K – b/c K inside cells; ↓serum hemoglobin; MCV is normal! We can’t change it quick! Dark urine – Hemoglobin;
RiskFactors
IsRedFlag
IsNPLEX
Consequence
ProgressionFromCondition
Sickle cell, Autoimmune hemolysis, Hereditary spherocytosis, PNH, G6PD deficiency;
TreatmentOptions
Transfusion; Hydration
PharmOptions
WebLink
https://www.merckmanuals.com/en-ca/professional/hematology-and-oncology/anemias-caused-by-hemolysis/overview-of-hemolytic-anemia
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