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Condition Info
ConditionName
Interstitial Lungs Disease
ConditionDescription
Inflammatory process involving the alveolar wall resulting in wide spread of irreversible fibrosis distortion of lung architecture and impaired gas exchange
Symptoms
Dyspnea; Non productive cough; Fatigue; History of RA, systemic sclerosis, SLE; Progressive exercise intolerance; Dyspnea;
PhysicalFindings
Dry crackles; JVD; Tachypnea; Possible digital clubbing;
ClinicalTests
UA; ANA; RF; xRay: Ground glass; CT better compare with x-ray;; Biopsy - gold standard, but not required for every pt: Fibrosis – shows stage of the dz; Spirometry - how bad is situation? xRay and CT – best initial tests (honeycomp); PFT: Restrictive lung dz ↓TLC ↓FRC ↓RV Decreased TLC, VC and normal or increased FEV1/FVC ratio; Lavage: Neutrophils; Loss of parenchymal architecture;
RiskFactors
>50 y/o; Pulmonary hypertension;
IsRedFlag
IsNPLEX
Consequence
Inflammatory process involving the alveolar wall resulting in wide spread of irreversible fibrosis distortion of lung architecture and impaired gas exchange
ProgressionFromCondition
Drugs (amiodarone, nitrofurantoin, phenytoin); Radiation on thoracic area; Occupations (berylliosis..); Mold exposure (farmer’s lungs);
TreatmentOptions
Lung transplantation;
PharmOptions
Sildenafil; Steroids; Antibiotics;
WebLink
https://www.merckmanuals.com/en-ca/professional/pulmonary-disorders/interstitial-lung-diseases/overview-of-interstitial-lung-disease
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