Condition Info - BotMed Application

ConditionName

Sepsis

ConditionDescription

Symptoms

Bacteremia->sepsis-> septic shock (+low BP) – systemic vasodilation -> ischemia 
Malaise, chills, nausea/vomiting
Symptoms of infection

PhysicalFindings

Fever;
Mental status changes;
Tachycardia (>90) tachypnea (20 /min);
Cold extremities (later);

ClinicalTests

Positive culture (as soon as possible):
Strep, Staph, Klebsiella, Pseudomonas, Neisseria m.
Candida;

UA -> UTI;
Chest xRay;

T: >38.3 or <36
Tachycardia (HR >90)
Tachypnea(>20)
WBC >12000
Leucopenia <4000

ABCs;
Elevated: BUN, creatinine. Bilirubin, lactate;

SOFA:
altered mental status;
RR>22;
SBP < 100;

Score >= 2 -> significant higher mortality risk;

Septic shock -> sepsis + lactate > 2 mmol/l

RiskFactors

Recent hospitalization, recent surgery, immunosuppression, age

IsRedFlag

IsNPLEX

Consequence

ProgressionFromCondition

SIRS (Systemic inflammatory response syndrome):
Pancreatitis
Thromboembolism
Surgery
Autoimmune disorder
NO INFECTION!

Asplenia 
IV rug users (stap A.)

TreatmentOptions

PharmOptions

IV hydration;
Norepinephrine;
Glucocorticoids (if adrenal insufficiency);
Antibiotics;
Glycemic control;

WebLink

https://www.merckmanuals.com/en-ca/professional/critical-care-medicine/sepsis-and-septic-shock/sepsis-and-septic-shock | https://www.aafp.org/afp/2013/0701/p44.html