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Condition Info
ConditionName
Liver cancer
ConditionDescription
Symptoms
RUQ abdominal pain; Weigh loss; Malaise; Anorexia; Diarrhea; Jaundice;
PhysicalFindings
Hepatomegaly; Bruit over the liver; Ascites;
ClinicalTests
↑Bilirubin; ↑ALP CT of chest/ab/pelvic; Colonoscopy; ↑AST, ALT; ↑alpha-fetoprotein (AFP) – marker of hepatocellular carcinoma (screening test); Abdominal US (screening test); Biopsy to confirm diagnosis – if no other way around!
RiskFactors
Chronic infection; Cholelithiasis; Biliary track dz; Hepatic adenoma (10%) b/c OCP intake; Hep B, C; Cirrhosis; Aflatoxin exposure ; Alcoholism ;
IsRedFlag
IsNPLEX
Consequence
Metastasis: breast, LU, colon cancer; Portal vein abstraction; Liver failure; Hypoglycemia; Excessive RBC production; Refractory watery diarrhea; Hypercalcemia; Various skin lesions;
ProgressionFromCondition
TreatmentOptions
Surgical resection; Transplant
PharmOptions
Chemo;
WebLink
https://www.merckmanuals.com/en-ca/professional/hepatic-and-biliary-disorders/liver-masses-and-granulomas/primary-liver-cancer
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