Condition Info - BotMed Application

ConditionName

Ulcerative colitis (IBD)

ConditionDescription

Symptoms

Fecal urgency; Tenesmus; Incontinence; Entirely mucosal, Ab tenderness, pain; Fatigue;
No fistulas, No abscesses; No obstruction; No anal problems
BLOODY DIARRHEA;

B/c of inflammation:
Arthralgia;
Uveitis;
Skin (erythema nodosum, pyoderma gangrenosum);
Liver dz;
Sclerosing cholangitis (more in UC);

PhysicalFindings

Fever, Blood on oral exam, Orthostatic hypotension, Tachycardia

ClinicalTests

Stool cultures and microscopy (to exclude infectious causes);
Colonoscope with biopsy;
Calprotectin stool test (IBS>50, IBD>150) --> not diagnostic;

CD:
ANCA: CD negative;
ASCA: CD positive;

UC:
ANCA: CD positive;
ASCA: CD negative;

RiskFactors

IsRedFlag

IsNPLEX

Consequence

Short term:
Hemorrhage;
Anemia;
Toxic megacolon;
Perforation;

Long term:
Strictures leading to obstructions;
Dysplasia leading to colon cancer after 10 years.
Osteoporosis; Vit D deficiency.

50% have both conditions!
Ankylosis spondylitis;

ProgressionFromCondition

TreatmentOptions

Curable by surgery
In addition to CD treatment:
Topical treatment with supp and enema
Iron for anemia

PharmOptions

Start with aminosalicylate (mesalamine);
Acute: steroids

WebLink

https://www.merckmanuals.com/en-ca/professional/gastrointestinal-disorders/inflammatory-bowel-disease-ibd/ulcerative-colitis?query=Ulcerative colitis