Condition Info - BotMed Application

ConditionName

Syphilis

ConditionDescription

Symptoms

Painless ulcer (1 stage)

Fever;
Malaise;
Lymphadenopathy- painless;
Rash (palms, soles, oral (condyloma latte);

Secondary:
Sore throat;
Fever;
Swollen lymph glands;
Headaches;
Fatigue;
Muscle aches;
Wart-like patches around skin folds or genitals;
Loss of appetite;
Joint pain;
Enlarged lymph nodes;

Tertiary syphilis;
CVD: aneurysms of ascending aorta;
Aortic valve insufficiency;
Gummas(granulomatous lesions in skin, bones, internal organs);
CNS: general paresis, tabes dorsalis (affects proprioception-> gait and balance), Argyll-Robertson pupil;

PhysicalFindings

Romberg test – test for Tabes dorsalis, not for cerebellum!

ClinicalTests

For primary: Dark field microscopy – best initial test;

RPR;
VDRL – screening test, not specific FTL Ab test - Trapinials testchlom;

False positive for Syphilis:
Mono;
Rheumatoid factor;
SLE;
Leprosy;
IV drug users;

RiskFactors

IsRedFlag

IsNPLEX

Consequence

ProgressionFromCondition

TreatmentOptions

PharmOptions

Penicillin G

1 and 2: IM
3: IV

WebLink

https://www.merckmanuals.com/en-ca/professional/infectious-diseases/sexually-transmitted-diseases-stds/syphilis