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Condition Info
ConditionName
Poststreptococcal glomerulonephritis
ConditionDescription
Symptoms
History of throat infection or skin infection (impetigo) by 1-3 weeks; Cola-colored urine; Edema (periorbital); HTN; Oliguria
PhysicalFindings
ClinicalTests
Best first test: UA; Dysmorphic RBC, RBC cast, proteinuria, hematouria 2nd test: ↑antistreptolysin O (ASO) titers; anti-DNAse Abs titers (others strep spices); Most accurate: Biopsy: deposit of IgG on basement membrane;
RiskFactors
IsRedFlag
IsNPLEX
Consequence
Renal failure -> Death
ProgressionFromCondition
Sore throat
TreatmentOptions
Treatment of strep will not prevent post-strep glomerulonephritis; Supportive
PharmOptions
Steroids; ACE inhibitors; Statins;
WebLink
https://www.merckmanuals.com/en-ca/professional/genitourinary-disorders/glomerular-disorders/rapidly-progressive-glomerulonephritis-rpgn
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