Condition Info - BotMed Application

ConditionName

Ankylosing spondylitis

ConditionDescription

Symptoms

Backpain in low back; 
Pain is worsening by rest and relive by activity;
Flattening of the normal lumbar curvature; Decreased chest expansion; Peripheral arthritis of knees, hips, shoulder (50%); 
Cardiac: atrioventricular block in 3% to 5%: aortic insufficiency; 
Chronic; inflammatory; large joints; symmetrical;

PhysicalFindings

Bending forward improve symptoms; 
Painful sacroiliac joints; 
Reduced spine mobility; 
Uveitis;

ClinicalTests

ESR elevated 85%;
CRP elevated; 
xray: Bamboo spine – fusion of vertebral joints – late finding;
Best initial test: xRay of SI joint (narrowing on the joint);
Most accurate test – MRI (very early can detect abnormalities);

(-)ANA;
(-)RF;

RiskFactors

2-40 y/o; 
Male, female, Caucasians; 
Klebsiella spp;
Arthritis;
Psoriasis;
Inflammatory bowel disease (IBD);
Uveitis;
Presence of HLA-B27;

IsRedFlag

IsNPLEX

Consequence

ProgressionFromCondition

TreatmentOptions

Exercises to increase mobility

PharmOptions

NSAIDs;
Adalimumab (if NSAIDs do not work);
Methotrexate;

WebLink

https://www.merckmanuals.com/en-ca/professional/musculoskeletal-and-connective-tissue-disorders/joint-disorders/ankylosing-spondylitis