Condition Info - BotMed Application

ConditionName

Wilson disease

ConditionDescription

Symptoms

Jaundice;
Golden-brown eye discoloration (Kayser-Fleischer rings, for 5-10% the first symptom);
Fluid buildup in the legs or abdomen;
Problems with speech, cognitive, psychiatric, swallowing or physical coordination;
Uncontrolled movements or muscle stiffness;
Hepatitis (for 50% of patients, mostly adolescents, the first symptom)

PhysicalFindings

Slit-lamp examination for Kayser-Fleischer rings;

ClinicalTests

Serum ceruloplasmin;
Sometimes serum copper, and 24-hour urinary copper excretion;
Sometimes confirmation by penicillamine provocation test or liver biopsy;

RiskFactors

IsRedFlag

IsNPLEX

Consequence

Cirrhosis;
Liver failure;
Death;
Persistent neurological problems;
Kidney problems;
Psychological problems;
Blood problems;

ProgressionFromCondition

TreatmentOptions

PharmOptions

WebLink

https://www.merckmanuals.com/professional/nutritional-disorders/mineral-deficiency-and-toxicity/wilson-disease