Condition Info - BotMed Application

ConditionName

Hepatitis C

ConditionDescription

Symptoms

Bleeding easily;
Bruising easily;
Fatigue;
Poor appetite;
Yellow discoloration of the skin and eyes (jaundice);
Dark-colored urine;
Itchy skin;
Fluid buildup in your abdomen (ascites);

PhysicalFindings

ClinicalTests

Hep C DNA PCR – best for determine viral replication activity;
ALT rise and fall after 6 m;
Serologic testing;

RiskFactors

Extrahepatic manifestations: 
Membranoproliferative GN;
Essential mixed cryoglobinemia;
Lymphoma;
Thyroiditis;
Porphyria;
Cutanea tarda;
Lichen planus;
DM;

Screening for hepatitis C
The U.S. Preventive Services Task Force recommends that all adults ages 18 to 79 years be screened for hepatitis C, even those without symptoms or known liver disease. Screening for HCV is especially important if you're at high risk of exposure, including:

Anyone who has ever injected or inhaled illicit drugs;
Anyone who has abnormal liver function test results with no identified cause;
Babies born to mothers with hepatitis C;
Health care and emergency workers who have been exposed to blood or accidental needle sticks;
People with hemophilia who were treated with clotting factors before 1987;
People who have undergone long-term hemodialysis treatments;
People who received blood transfusions or organ transplants before 1992;
Sexual partners of anyone diagnosed with hepatitis C infection;
People with HIV infection;
Anyone born from 1945 to 1965;
Anyone who has been in prison;

IsRedFlag

IsNPLEX

Consequence

80% have infection chronically;
50% cirrhosis;
Hepatocellular carcinoma;
Persistent carrier state;

ProgressionFromCondition

TreatmentOptions

PharmOptions

Interferon alpha

WebLink

https://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/hepatitis/hepatitis-c-acute